Biological Availability

Soy polysaccharide as a novel superdisintegrant in sildenafil citrate sublingual tablets: preparation, characterization, and in vivo evaluation

Pharmaceutical Technology / Polysaccharides / Pharmaceutical Chemistry / Humans / Wettability / Male / Hardness / Solubility / Phosphodiesterase Inhibitors / Soybeans / Adult / Tablets / Excipients / Drug Stability / Biological Availability / Male / Hardness / Solubility / Phosphodiesterase Inhibitors / Soybeans / Adult / Tablets / Excipients / Drug Stability / Biological Availability

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Anaemia and iron deficiency disease in children

Biology / Vitamin A / Humans / Child / Infant / Incidence / Newborn Infant / Parasitic Diseases / Iron Deficiency Anemia / Biological Availability / Nino / Incidence / Newborn Infant / Parasitic Diseases / Iron Deficiency Anemia / Biological Availability / Nino

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Preparation and characterization of spironolactone-loaded nano-emulsions for extemporaneous applications

Scanning Electron Microscopy / Crystallization / Nanoparticles / Drug development / Pharmaceutical Chemistry / Oils / Pharmaceutics / Differential scanning calorimetry / Diuretics / Solubility / Chemical Precipitation / Particle Size / Fats / Surface Active Agents / Water soluble polymers / Solid Dispersion / Microspheres / Spray Drying / Drug Carriers / Excipients / Biological Availability / Polyethylene Glycols / Solvents / Oils / Pharmaceutics / Differential scanning calorimetry / Diuretics / Solubility / Chemical Precipitation / Particle Size / Fats / Surface Active Agents / Water soluble polymers / Solid Dispersion / Microspheres / Spray Drying / Drug Carriers / Excipients / Biological Availability / Polyethylene Glycols / Solvents

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Enantiospecific ketoprofen concentrations in plasma after oral and intramuscular administration in growing pigs

Animal Production / Female / Animals / Male / Tandem Mass Spectrometry / High Performance Liquid Chromatography / Shell Half-Life / Swine / Veterinary Sciences / Biological Availability / Cross-Over Studies / Area Under Curve / High Performance Liquid Chromatography / Shell Half-Life / Swine / Veterinary Sciences / Biological Availability / Cross-Over Studies / Area Under Curve

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Effect of PF-04217329 a prodrug of a selective prostaglandin EP2 agonist on intraocular pressure in preclinical models of glaucoma

Pharmacology / Quantum Physics / Calcium / Pharmacokinetics / Cornea / Dogs / Prodrugs / Humans / cyclic AMP / Glaucoma / Animals / Male / Intraocular Pressure / Optometry and Ophthalmology / Topical Drug Administration / Clinical Study / Macaca fascicularis / Iris / Rabbits / Visual Field / Biological Availability / Ophthalmic Solutions / Neurosciences / Prostaglandin E2 / Primary Open Angle Glaucoma / Dogs / Prodrugs / Humans / cyclic AMP / Glaucoma / Animals / Male / Intraocular Pressure / Optometry and Ophthalmology / Topical Drug Administration / Clinical Study / Macaca fascicularis / Iris / Rabbits / Visual Field / Biological Availability / Ophthalmic Solutions / Neurosciences / Prostaglandin E2 / Primary Open Angle Glaucoma

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Effect of PF-04217329 a prodrug of a selective prostaglandin EP(2) agonist on intraocular pressure in preclinical models of glaucoma

Pharmacology / Quantum Physics / Calcium / Pharmacokinetics / Cornea / Dogs / Prodrugs / Humans / cyclic AMP / Glaucoma / Animals / Male / Intraocular Pressure / Optometry and Ophthalmology / Topical Drug Administration / Clinical Study / Macaca fascicularis / Iris / Rabbits / Visual Field / Biological Availability / Ophthalmic Solutions / Neurosciences / Prostaglandin E2 / Primary Open Angle Glaucoma / Dogs / Prodrugs / Humans / cyclic AMP / Glaucoma / Animals / Male / Intraocular Pressure / Optometry and Ophthalmology / Topical Drug Administration / Clinical Study / Macaca fascicularis / Iris / Rabbits / Visual Field / Biological Availability / Ophthalmic Solutions / Neurosciences / Prostaglandin E2 / Primary Open Angle Glaucoma

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Efecto de la nebulización dirigida de fármacos en la administración pulmonar

Anthropometry / Aerosols / Humans / Charcoal / Male / Young Adult / Drug Delivery Systems / Lung / Clinical Sciences / Spirometry / Adult / Radiopharmaceuticals / Biological Availability / Equipment Design / Cross-Over Studies / Respiratory Care / Young Adult / Drug Delivery Systems / Lung / Clinical Sciences / Spirometry / Adult / Radiopharmaceuticals / Biological Availability / Equipment Design / Cross-Over Studies / Respiratory Care

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Tryptophan 2,3-Dioxygenase (TDO) Inhibitors. 3-(2-(Pyridyl)ethenyl)indoles as Potential Anticancer Immunomodulators

Organic Chemistry / Medicinal Chemistry / Kinetics / Enzyme Inhibitors / Cell line / Humans / Mice / Animals / Drug Design / Medicinal / Neoplasms / Structure activity Relationship / Biological Availability / Antineoplastic Agents / Humans / Mice / Animals / Drug Design / Medicinal / Neoplasms / Structure activity Relationship / Biological Availability / Antineoplastic Agents

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Biologically erodable microspheres as potential oral drug delivery systems

Electron Microscopy / Drug delivery / Drug Delivery System / Polymers / Multidisciplinary / Nature / Blood Glucose / Insulin / Intestinal Mucosa / Gene transfer techniques / Drug Delivery Systems / Plasmids / Delivery System / Biological activity / Microspheres / Biological Availability / Engineering Polymers / Area Under Curve / Plasmid DNA / Nature / Blood Glucose / Insulin / Intestinal Mucosa / Gene transfer techniques / Drug Delivery Systems / Plasmids / Delivery System / Biological activity / Microspheres / Biological Availability / Engineering Polymers / Area Under Curve / Plasmid DNA

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Comparison of two compartmental models for describing ranitidine\'s plasmatic profiles

Humans / Animals / Male / Statistical Significance / High Pressure Liquid Chromatography / Intestinal absorption / Rats / Adult / Biotransformation / Gastrointestinal Tract / Wistar Rats / Pharmacological / Statistical Test / Ranitidine / Biological Availability / Area Under the Curve / Area Under Curve / Bile / Intestinal absorption / Rats / Adult / Biotransformation / Gastrointestinal Tract / Wistar Rats / Pharmacological / Statistical Test / Ranitidine / Biological Availability / Area Under the Curve / Area Under Curve / Bile

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Preliminary pharmaceutical development of antimalarial-antibiotic cotherapy as a pre-referral paediatric treatment of fever in malaria endemic areas

Malaria / Pharmaceutical Technology / Powder Diffraction / Crystallization / Pharmaceutical Chemistry / Macromolecular X-Ray Crystallography / Pharmaceutics / Humans / Animals / Endemic Diseases / Solubility / Anti-Bacterial Agents / Antimalarials / Tablets / Age Factors / Rabbits / Azithromycin / Capsules / Excipients / Biological Availability / Macromolecular X-Ray Crystallography / Pharmaceutics / Humans / Animals / Endemic Diseases / Solubility / Anti-Bacterial Agents / Antimalarials / Tablets / Age Factors / Rabbits / Azithromycin / Capsules / Excipients / Biological Availability

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The loading history of trace metals and nutrients in Altata-Ensenada del Pabellón, lagoon complex, northwestern Mexico

Geology / Agricultural Development / Trace Metals / Mexico / Biological Sciences / Heavy metals / Environmental Sciences / Urban Growth / Environmental Radioactivity / Stable Isotope / Animals / Coastal lagoon / Seawater / Trace Elements / Anthropogenic impact / CHEMICAL SCIENCES / Ecosystem / MEXICO / Water Movements / Organic Matter / Food Chain / Environmental / Biological Availability / Geologic Sediments / Heavy metals / Environmental Sciences / Urban Growth / Environmental Radioactivity / Stable Isotope / Animals / Coastal lagoon / Seawater / Trace Elements / Anthropogenic impact / CHEMICAL SCIENCES / Ecosystem / MEXICO / Water Movements / Organic Matter / Food Chain / Environmental / Biological Availability / Geologic Sediments

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The loading history of trace metals and nutrients in Altata-Ensenada del Pabellón, lagoon complex, northwestern Mexico

Geology / Agricultural Development / Trace Metals / Mexico / Biological Sciences / Heavy metals / Environmental Sciences / Urban Growth / Environmental Radioactivity / Stable Isotope / Animals / Coastal lagoon / Seawater / Trace Elements / Anthropogenic impact / CHEMICAL SCIENCES / Ecosystem / MEXICO / Water Movements / Organic Matter / Food Chain / Environmental / Biological Availability / Geologic Sediments / Heavy metals / Environmental Sciences / Urban Growth / Environmental Radioactivity / Stable Isotope / Animals / Coastal lagoon / Seawater / Trace Elements / Anthropogenic impact / CHEMICAL SCIENCES / Ecosystem / MEXICO / Water Movements / Organic Matter / Food Chain / Environmental / Biological Availability / Geologic Sediments

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Poly- -Caprolactone Intravitreous Devices: An In Vivo Study

Scanning Electron Microscopy / Drug delivery / Biological Sciences / Dexamethasone / Animals / Feasibility Studies / Intraocular Pressure / High Pressure Liquid Chromatography / Shell Half-Life / Rabbits / Polyesters / Biocompatible Materials / Drug Carriers / Biological Availability / Feasibility Studies / Intraocular Pressure / High Pressure Liquid Chromatography / Shell Half-Life / Rabbits / Polyesters / Biocompatible Materials / Drug Carriers / Biological Availability

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Plasma tocopherol concentrations in response to supplemental vitamin E

Engineering / Humans / Female / Male / American / Vitamin E / Middle Aged / Adult / Biological Availability / Vitamin E / Middle Aged / Adult / Biological Availability

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Nitric oxide deficiency promotes vascular side effects of cyclooxygenase inhibitors

Humans / Mice / Nitric oxide / Animals / Blood / Male / Arthritis / Vasoconstriction / Platelet activation mechanism / Inflammatory disease / Clinical Sciences / Adverse Event / Side Effect / Pyrazoles / Aorta / Biological Availability / Healthy Subjects / Indomethacin / Male / Arthritis / Vasoconstriction / Platelet activation mechanism / Inflammatory disease / Clinical Sciences / Adverse Event / Side Effect / Pyrazoles / Aorta / Biological Availability / Healthy Subjects / Indomethacin

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